版主管理 | 推荐 | 删除 | 删除并扣分
E for patients admitted on the SICU with ventilator support.P
E for individuals admitted to the SICU with ventilator assist.P49 Soluble triggering receptor expressed on purchase KU-0063794 myeloid cells-1 in bronchoalveolar lavage is not really predictive for ventilatorassociated pneumoniaG Oudhuis, J Beuving, J Zwaveling, D Bergmans, EE Stobberingh, G 10 Velde, C Linssen, A Verbon University Hospital Maastricht, The Netherlands Critical Treatment 2008, 12(Suppl 2):P49 (doi: 10.1186/cc6270) Introduction The intention of the research was to evaluate the usefulness of soluble triggering PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25582226 receptor expressed on myeloid cells-1 (sTREM-1) for a speedy diagnostic take a look at for ventilator-associated pneumonia (VAP). sTREM-1 in BALF was calculated working with a quantitative sandwich enzyme immunoassay. Two researchers, unaware of your outcomes of your assay, determined no matter whether a VAP was present. Clinical suspicion of a VAP was verified through the existence of 2 cells made up of intracellular organisms and/or a quantitative lifestyle results of >104 colony forming units/ml in BALF. The disorder had to be acquired immediately after at the least forty eight hours of mechanical ventilation. Effects The signify concentration of sTREM-1 was appreciably bigger in BALF of PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25064496 people with verified VAP in comparison with sufferers with no VAP (P = 0.045). The world beneath the curve was 0.577 (95 CI = 0.503?.651, P = 0.042). sTREM-1 ranges within our arms proved not to be discriminative for VAP. Selecting a sensitivity of 95 resulted in the constructive predictive worth (PPV) of forty one along with a negative predictive benefit (NPV) of 62 within our inhabitants. Using a specificity of ninety five triggered a PPV of sixty seven as well as a NPV of sixty two . sTREM-1 levels were not diverse in VAP scenarios caused by Gram-positive or Gram-negative micro organism. sTREM-1 concentrations have been higher in nonsurvivors in contrast with survivors, about inhospital mortality. Conclusions The outcomes suggest the sTREM-1 assay in BALF is not really discriminative for VAP. References one. Jackson WL, et al.: Curr Opin Anaesthesiol 2006, 19:117-121. two. Bouchon A, et al.: Character 2001, 410:1103-1107. three. Gibot S, et al.: N Engl J Med 2004, 350:451-458.Introduction Ventilator-associated pneumonia (VAP) is easily the most vital ICU-acquired infection in mechanically ventilated sufferers that seems forty eight?two hours soon after the beginning of mechanical ventilation. The aim of the review was to evaluate the incidence and microbiology of VAP and to compare two quantitative bronchoscopic procedures ?bronchoalveolar lavage (BAL) and bronchoscopic tracheobronchical secretion (TBS) ?for that prognosis. Approaches The epidemiological and microbiological etiology of VAP in a very surgical ICU with 65 sufferers through a 1-year period was evaluated in this particular possible open up, medical review. The sufferers were being divided into two teams: group I, 30 clients with mechanical air flow for a longer period than forty eight hrs with VAP (the situation groups); team II, 35 clients with mechanical ventilation for a longer time than forty eight hours without having VAP (the command group). Two different types of quantitative bronchoscopic strategies for determining the etiological agent were being when compared (BAL and TBS).
2019-9-9 09:52:33 BY 游客   查看:61 次   以下共有回复:0 篇  
共0篇回复 每页10篇 页次:1/1
我要回复
回复内容
验 证 码
看不清?更换一张
匿名发表 

地 址:山东省海阳市海滨西路市政府对面亚沙水生植物园     电话:18661998752     版权所有:山东泓莹旅游开发有限公司